Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214065 | 0.95 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9301854 | 0.87 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9301837 | 0.87 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL397519 | 0.87 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11113106 | 0.86 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL393193 | 0.85 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL395576 | 0.85 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3622054 | 0.83 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16070946 | 0.82 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15355891 | 0.81 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500695-A | Silicone-vinyl acetate composition for contact lenses | IVANI EDWARD J | 1985-02-19 | — | — | US | claimed |
| US-4500628-A | IRRADIATING FILM CONSISTING OF POLYMER AND ORGANOSILICON MONOMER | AT&T BELL LABORATORIES (US) | 1985-02-19 | — | — | US | claimed |
| US-4410674-A | Silicone-vinyl acetate composition for contact lenses | IVANI EDWARD J | 1983-10-18 | — | — | US | claimed |
| EP-3090007-B1 | CONTACT LENSES MADE WITH HEMA-COMPATIBLE POLYSILOXANE MACROMERS | COOPERVISION INT HOLDING CO LP (BB) | 2017-06-07 | — | — | EP | disclosed |
| US-9574038-B2 | Contact lenses made with HEMA-compatible polysiloxane macromers | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2017-02-21 | — | — | US | disclosed |
| US-20170008990-A1 | Contact Lenses Made With HEMA-Compatible Polysiloxane Macromers | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2017-01-12 | — | — | US | disclosed |
| EP-3090007-A1 | CONTACT LENSES MADE WITH HEMA-COMPATIBLE POLYSILOXANE MACROMERS | CooperVision International Holding Company, LP (BB) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015128636-A1 | CONTACT LENSES MADE WITH HEMA-COMPATIBLE POLYSILOXANE MACROMERS | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2015-09-03 | — | — | WO | disclosed |
| EP-1902835-B1 | Multilayer decorative film | DECEUNINCK NV (BE) | 2013-03-13 | — | — | EP | disclosed |
| WO-2008037637-A2 | MULTILAYER DECORATIVE FILM | DECEUNINCK NV (BE) | 2008-04-03 | — | — | WO | disclosed |
| EP-1902835-A1 | Multilayer decorative film | Deceuninck NV (BE) | 2008-03-26 | — | — | EP | disclosed |
| US-4500695-A | Silicone-vinyl acetate composition for contact lenses | IVANI EDWARD J | 1985-02-19 | — | — | US | disclosed |
| US-4410674-A | Silicone-vinyl acetate composition for contact lenses | IVANI EDWARD J | 1983-10-18 | — | — | US | disclosed |
| US-4355147-A | ESPECIALLY CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1982-10-19 | — | — | US | disclosed |
| EP-0060015-A1 | Polysiloxane with cycloalkyl modifier composition and biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 1982-09-15 | — | — | EP | disclosed |
| EP-0059528-A1 | Polysiloxane with polycyclic modifier composition and biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 1982-09-08 | — | — | EP | disclosed |
| EP-0059529-A1 | Polysiloxane composition and biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 1982-09-08 | — | — | EP | disclosed |
| US-4341889-A | Polysiloxane composition and biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 1982-07-27 | — | — | US | disclosed |
| US-4327203-A | Polysiloxane with cycloalkyl modifier composition and biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 1982-04-27 | — | — | US | disclosed |
| US-4277595-A | HYDROPHILIC, SOFT, FLEXIBLE, OXYGEN TRANSPORT, NONHYDROLYZING, CROSSLINKED NETWORK | BAUSCH & LOMB INCORPORATED (US) | 1981-07-07 | — | — | US | disclosed |