Sugi Predict

Sugi Predict / Compounds / SCHEMBL214065

SCHEMBL214065

SCHEMBL214065

C=C(C)C(=O)OCCC[Si](C)(CCCOC(=O)C(=C)C)O[Si](C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 4/20 0.51
▸ THRB P10828 1/20 0.44
▸ POLB P06746 1/20 0.40
▸ APEX1 P27695 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.39
▸ HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4727115 0.95 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11113106 0.91 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL35612 0.86 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL12094871 0.86 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL35807 0.86 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL35511 0.86 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL10942627 0.85 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL393256 0.85 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL395578 0.85 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9715028 0.85 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2187243-B2 Colored ink for pad transfer printing of silicone hydrogel lenses ALCON INC (CH) 2025-07-09 — — EP claimed
CN-118325262-A Impact-resistant polymer composite material for high-speed motor train and preparation method thereof 中铁伟业（北京）新技术有限公司 2024-07-12 — — CN claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 — — EP claimed
CN-116327738-A Patch containing cannabidiol 宝泓生医股份有限公司 2023-06-27 — — CN claimed
CN-116315071-A Wide-temperature solid electrolyte 上海交通大学绍兴新能源与分子工程研究院 2023-06-23 — — CN claimed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 — — US claimed
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 — — EP claimed
CN-113166340-A Hydrogel composition 眼科公司 2021-07-23 — — CN claimed
EP-3598181-B1 VINYLIC MONOMER AND PREPOLYMER COMPRISING SAME ALCON INC (CH) 2021-06-23 — — EP claimed
WO-2020070423-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2020-04-09 — — WO claimed
EP-0455585-A1 Unsaturated urea polysiloxanes CIBA-GEIGY AG (CH) 1991-11-06 — — EP claimed
US-4820747-A ACRYLATED CROSSLINKED POLYSILOXANES FORM HARD, HYDROPHILIC, DISPOSABLE, EXTENDED-WEAR LENSES OCULAR TECHNOLOGIES, INC. (US) 1989-04-11 — — US claimed
EP-0295947-A2 Gas permeable contact lens and method and materials for its manufacture OCULAR TECHNOLOGIES INC. (US) 1988-12-21 — — EP claimed
US-4666249-A Surface-treated contact lens and method of producing SOLA U.S.A. INC. (US) 1987-05-19 — — US claimed
EP-0216074-A2 Polyvinyl alcohol derivatives and crosslinked hydrogel contact lenses made therefrom CIBA-GEIGY AG (CH) 1987-04-01 — — EP claimed
EP-0174368-A1 SILICONE HYDRIDE CONTACT LENS AND POLYMER MC CARRY, John D. (US) 1986-03-19 — — EP claimed
WO-1985003940-A1 SILICONE HYDRIDE CONTACT LENS AND POLYMER MC CARRY, JOHN, D. (US) 1985-09-12 — — WO claimed
US-4507452-A HIGH OXYGEN PERMEABILITY, REDUCED TENDENCY FOR BIOLOGICAL CONTAMIN McCarry, John D. (US) 1985-03-26 — — US claimed
EP-0108886-A2 Silicone-containing hard contact lens materials having increased oxygen permeability CIBA-GEIGY AG (CH) 1984-05-23 — — EP claimed
US-4400333-A Production of oxygen permeable contact lenses NEEFE OPTICAL LABORATORY 1983-08-23 — — US claimed