SCHEMBL397519

SCHEMBL397519

C=C(C)C(=O)OCCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.54
THRB P10828 1/20 0.43
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 3/20 0.38
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL393193 0.98 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL395576 0.98 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL35807 0.95 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL333002 0.93 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11312974 0.90 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9418354 0.90 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
Methacrylic Acid SCHEMBL29583152 0.90 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
Methacrylic Acid SCHEMBL15856026 0.90 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11312944 0.90 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11157535 0.90 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12147192-B2 Carrier for developing electrostatic latent image, two-component developer, image forming apparatus, process cartridge, and image forming method RICOH COMPANY, LTD. (JP) 2024-11-19 US disclosed
US-20220291603-A1 CARRIER FOR DEVELOPING ELECTROSTATIC LATENT IMAGE, TWO-COMPONENT DEVELOPER, IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2022-09-15 US disclosed
US-11427666-B2 Silicone-containing acrylic polymers for transdermal drug delivery compositions NOVEN PHARMACEUTICALS, INC. (US) 2022-08-30 US disclosed
US-20200277424-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMACEUTICALS, INC. (US) 2020-09-03 US disclosed
EP-3179989-B1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMA (US) 2019-06-12 EP disclosed
EP-3179989-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS Noven Pharmaceuticals, INC. (US) 2017-06-21 EP disclosed
US-20160030362-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMACEUTICALS, INC. (US) 2016-02-04 US disclosed
WO-2016018858-A1 SILICONE-CONTAINING ACRYLIC POLYMERS FOR TRANSDERMAL DRUG DELIVERY COMPOSITIONS NOVEN PHARMACEUTICALS, INC. (US) 2016-02-04 WO disclosed
US-20140362339-A1 SILICONE HYDROGEL SOFT CONTACT LENS HAVING WETTABLE SURFACE HOYA CORPORATION (JP) 2014-12-11 US disclosed
US-8877418-B2 Developing method and image forming method RICOH COMPANY, LTD. (JP) 2014-11-04 US disclosed
US-8110697-B2 Method for the production of polymerizable silicones WACKER CHEMIE AG (DE) 2012-02-07 US disclosed
US-20120028183-A1 DEVELOPING METHOD AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2012-02-02 US disclosed
US-8101789-B2 Method for the production of polymerizable silicones WACKER CHEMIE AG (DE) 2012-01-24 US disclosed
EP-2125833-B1 METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES WACKER CHEMIE AG (DE) 2010-08-25 EP disclosed
EP-2125834-B1 METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES WACKER CHEMIE AG (DE) 2010-08-25 EP disclosed
US-20100041909-A1 METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES WACKER CHEMIE AG (DE) 2010-02-18 US disclosed
US-20100029972-A1 METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES WACKER CHEMIE AG (DE) 2010-02-04 US disclosed
US-5376378-A Transdermal drug delivery CIBA-GEIGY CORP. (US) 1994-12-27 US disclosed
US-5288827-A Drug selivery CIBA-GEIGY CORPORATION (US) 1994-02-22 US disclosed