Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 10/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776859 | 0.77 | PIK3R1 (0.45) | SCD5PIK3R1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL4778809 | 0.76 | EPHX2 (0.39) | SCD5PIK3R1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL3325803 | 0.70 | PKM (0.41) | SCD5USP30PKM | |
| SCHEMBL31382091 | 0.70 | PKM (0.48) | SCD5PKM | |
| SCHEMBL3325807 | 0.68 | GPR119 (0.41) | SCD5USP30PKM | |
| SCHEMBL207984 | 0.67 | CHRM2 (0.44) | SCD5KDM4EALDH1A1 | |
| SCHEMBL19625229 | 0.66 | EPHX2 (0.39) | PIK3R1PIK3CAPIK3CDPIK3CBUSP30 | |
| SCHEMBL5568440 | 0.66 | HDAC2 (0.37) | SCD5PIK3R1PIK3CA | |
| SCHEMBL4780264 | 0.66 | NPFFR1 (0.48) | — | |
| SCHEMBL4780268 | 0.66 | NPFFR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051419-A1 | AMINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. | 2008-02-28 | — | — | US | disclosed |
| WO-2008012635-A2 | AMINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PRODUCTS INC. (US) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051419-A1 | AMINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | CCNY, CCND2, CCND1 | SCD5 2749/4885PIK3R1 1643/4885PIK3CA 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.