Acetic Acid

Acetic Acid

SCHEMBL472754

CC(=O)O.Cc1c(N)c2ccccc2oc1=O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.60
GAA P10253 10/20 0.59
KDM4E B2RXH2 6/20 0.59
ALDH1A1 P00352 3/20 0.59
MGAM O43451 4/20 0.55
SI P14410 4/20 0.55
MGAM2 Q2M2H8 4/20 0.55
MAPT P10636 5/20 0.50
NPC1 O15118 2/20 0.50
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 2/20 0.49
AHR P35869 1/20 0.49
RAB9A P51151 1/20 0.49
ALOX15 P16050 1/20 0.48
HPGD P15428 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94134 0.92 GAA (0.69) POLBGAAKDM4EALDH1A1MGAM
Acetic Acid SCHEMBL4004465 0.87 GAA (0.59) POLBGAAKDM4EALDH1A1MGAM
Acetic Acid SCHEMBL15653002 0.86 KDM4E (0.66) POLBKDM4EALDH1A1MAPTNPC1
SCHEMBL29515065 0.78 GAA (0.69) POLBGAAKDM4EALDH1A1MGAM
SCHEMBL565925 0.78 GAA (0.69) POLBGAAKDM4EALDH1A1MGAM
SCHEMBL24199378 0.77 CA12 (0.66) POLBGAAKDM4EALDH1A1MAPT
SCHEMBL19285589 0.77 GAA (0.62) POLBGAAKDM4EALDH1A1MGAM
SCHEMBL2450078 0.77 KDM4E (0.71) GAAKDM4EALDH1A1MAPTCA12
Hydrochloric Acid SCHEMBL29609753 0.76 GAA (0.67) POLBGAAKDM4EALDH1A1MGAM
Bromide SCHEMBL25420644 0.76 GAA (0.67) POLBGAAKDM4EALDH1A1MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12146891-B2 United states systems and methods for fluid and component handling LABRADOR DIAGNOSTICS LLC (US) 2024-11-19 US disclosed
US-12085583-B2 Systems and methods for multi-analysis LABRADOR DIAGNOSTICS LLC (US) 2024-09-10 US disclosed
US-12054791-B2 Pathogen and antimicrobial resistance testing LABRADOR DIAGNOSTICS LLC (US) 2024-08-06 US disclosed
EP-4220120-A2 SYSTEMS AND METHODS FOR MULTI-ANALYSIS Labrador Diagnostics LLC (US) 2023-08-02 EP disclosed
EP-3189154-B1 PATHOGEN AND ANTIMICROBIAL RESISTANCE TESTING LABRADOR DIAGNOSTICS LLC (US) 2023-03-22 EP disclosed
EP-2956754-B1 SYSTEMS AND METHODS FOR MULTI-ANALYSIS LABRADOR DIAGNOSTICS LLC (US) 2023-01-11 EP disclosed
US-11524299-B2 Systems and methods for fluid handling LABRADOR DIAGNOSTICS LLC (US) 2022-12-13 US disclosed
US-20220170951-A1 SYSTEMS AND METHODS FOR MULTI-ANALYSIS LABRADOR DIAGNOSTICS LLC 2022-06-02 US disclosed
US-20210382077-A1 SYSTEMS AND METHODS FOR MULTI-ANALYSIS LABRADOR DIAGNOSTICS LLC 2021-12-09 US disclosed
US-20210341500-A1 FLUID HANDLING APPARATUS AND CONFIGURATIONS LABRADOR DIAGNOSTICS LLC 2021-11-04 US disclosed
US-6294331-B1 Methods for assessing genetic and phenotypic markers by simultaneous multicolor visualization of chromogenic dyes using brightfield microscopy and spectral imaging THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 2001-09-25 US disclosed
WO-2001055170-A1 MOB-5/HMOB-5 AS A CANCER DIAGNOSTIC MARKER VANDERBILT UNIVERSITY (US) 2001-08-02 WO disclosed
WO-2000060119-A2 METHODS FOR DETECTING CANCER CELLS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2000-10-12 WO disclosed
US-5843404-A Immunogenic conjugates of nitroaromatic compounds and proteins; monoclonal antibodies specific for nitroaromatic compounds , their protein conjugates TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1998-12-01 US disclosed
EP-0870055-A2 METHOD FOR DETECTING MULTIPLE COPIES OF A REPEAT SEQUENCE IN A NUCLEIC ACID MOLECULE LANSDORP, Peter, M. (CA) 1998-10-14 EP disclosed
WO-1997014026-A2 METHOD FOR DETECTING MULTIPLE COPIES OF A REPEAT SEQUENCE IN A NUCLEIC ACID MOLECULE DAKO A/S (DK) 1997-04-17 WO disclosed
EP-0669913-A4 DETECTION OF HYPOXIA. UNIV PENNSYLVANIA (US) 1996-08-21 EP disclosed
US-5540908-A DETECTION OF OXYGEN DEPRIVATION USING IMMUNOHISTOLOGICAL METHODS THE TRUSTEES OF THE UNIV. OF PENNSYLVANIA (US) 1996-07-30 US disclosed
EP-0669913-A1 DETECTION OF HYPOXIA THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1995-09-06 EP disclosed
WO-1994011348-A1 DETECTION OF HYPOXIA THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1994-05-26 WO disclosed