Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.66 |
| ▸ | CA9 | Q16790 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15842273 | 0.86 | CA12 (0.75) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| Acetic Acid SCHEMBL15653002 | 0.82 | KDM4E (0.66) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9657351 | 0.80 | CYP2C19 (0.63) | CA12CA9MAPTNPC1RAB9A | |
| SCHEMBL24358817 | 0.80 | CA12 (0.67) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28525823 | 0.80 | CA12 (0.62) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3527681 | 0.79 | CA12 (1.00) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30933370 | 0.79 | CA12 (1.00) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2450078 | 0.79 | KDM4E (0.71) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27872231 | 0.79 | HSD17B3 (0.71) | CA12CA9KDM4EALDH1A1MAPT | |
| SCHEMBL26339996 | 0.79 | MAOA (0.53) | CA12CA9KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225480-B2 | Malic enzyme inhibitors | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2022-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11225480-B2 | Malic enzyme inhibitors | ME1, RNASE1, ME2 | CA12 315/4885CA9 72/4885KDM4E 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.