Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741522 | 0.90 | NR1H4 (0.44) | NR1H4ELANECTSD | |
| SCHEMBL5707135 | 0.90 | NR1H4 (0.42) | NR1H4ELANECTSD | |
| SCHEMBL5691316 | 0.89 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL4783554 | 0.89 | NR1H4 (0.43) | NR1H4ELANECTSD | |
| SCHEMBL4729688 | 0.89 | NR1H4 (0.43) | NR1H4ELANECTSD | |
| SCHEMBL6629929 | 0.88 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL4617561 | 0.88 | NR1H4 (0.42) | NR1H4ELANECTSD | |
| SCHEMBL6527603 | 0.87 | NR1H4 (0.45) | NR1H4ELANECTSD | |
| SCHEMBL4662900 | 0.87 | NR1H4 (0.42) | NR1H4ELANECTSD | |
| SCHEMBL4782192 | 0.87 | NR1H4 (0.42) | NR1H4ELANECTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039829-A2 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-04-03 | — | — | WO | disclosed |
| EP-1478368-A1 | USE OF BENZOTHIAZEPINES HAVING ACTIVITY AS INHIBITORS OF ILEAL BILE ACID TRANSPORT FOR REDUCING CHOLESTEROLOLEMIA | Astrazeneca AB (SE) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003061663-A1 | USE OF BENZOTHIAZEPINES HAVING ACTIVITY AS INHIBITORS OF ILEAL BILE ACID TRANSPORT FOR REDUCING CHOLESTEROLOLEMIA | ASTRAZENECA AB (SE) | 2003-07-31 | — | — | WO | disclosed |