Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 0.68 |
| ▸ | HTR2A | P28223 | 19/20 | 0.68 |
| ▸ | HTR1A | P08908 | 18/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728203 | 0.97 | DRD2 (0.68) | DRD2HTR2AHTR1AKCNH2SLC6A4 | |
| SCHEMBL4729757 | 0.93 | DRD2 (0.71) | DRD2HTR2AHTR1AKCNH2SLC6A4 | |
| SCHEMBL4729092 | 0.90 | DRD2 (0.70) | DRD2HTR2AHTR1AKCNH2SLC6A4 | |
| SCHEMBL4729913 | 0.87 | DRD2 (0.71) | DRD2HTR2AHTR1AKCNH2SLC6A4 | |
| SCHEMBL4726611 | 0.87 | DRD2 (0.54) | DRD2HTR2AHTR1AKCNH2SLC6A4 | |
| SCHEMBL4726608 | 0.86 | HTR1A (0.71) | DRD2HTR2AHTR1AKCNH2SLC6A4 | |
| SCHEMBL4725836 | 0.86 | DRD2 (0.67) | DRD2HTR2AHTR1AKCNH2SLC6A4 | |
| SCHEMBL4727280 | 0.84 | DRD2 (0.71) | DRD2HTR2AHTR1AKCNH2SLC6A4 | |
| SCHEMBL4726778 | 0.84 | HTR2A (0.49) | DRD2HTR2AHTR1AKCNH2SLC6A4 | |
| SCHEMBL4729259 | 0.83 | DRD2 (0.70) | DRD2HTR2AHTR1AKCNH2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020306-A2 | ISOINDOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | claimed |