Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 8/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815467 | 0.78 | PARP1 (0.40) | PARP1PNMT | |
| SCHEMBL13833540 | 0.76 | PARP1 (0.47) | PARP1HTR5ACA1CA2CA7 | |
| SCHEMBL31176882 | 0.72 | POLB (0.40) | PARP1 | |
| SCHEMBL7333093 | 0.72 | CA12 (0.41) | ACHEBCHECA12CA1CA2 | |
| SCHEMBL28067181 | 0.72 | PARP1 (0.47) | PARP1HTR5APNMT | |
| SCHEMBL14820465 | 0.72 | PARP1 (0.47) | PARP1 | |
| SCHEMBL30584471 | 0.72 | CA12 (0.41) | ACHEBCHECA12CA1CA2 | |
| SCHEMBL16154709 | 0.71 | PARP1 (0.43) | PARP1CA2 | |
| SCHEMBL25639017 | 0.71 | PARP1 (0.43) | PARP1CA1CA2 | |
| SCHEMBL8729417 | 0.69 | ACHE (0.45) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020180-A2 | METHODS OF INCREASING THE SENSITIVITY OF CANCER CELLS TO DNA DAMAGE | KUDOS PHARMACEUTICALS LIMITED (GB) | 2008-02-21 | — | — | WO | disclosed |