Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.53 |
| ▸ | PPARA | Q07869 | 16/20 | 0.53 |
| ▸ | PPARD | Q03181 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727907 | 0.93 | PPARG (0.56) | PPARGPPARAPPARDPOLB | |
| SCHEMBL4726343 | 0.90 | PPARG (0.53) | PPARGPPARAPPARDPOLB | |
| SCHEMBL4728134 | 0.87 | PPARG (0.58) | PPARGPPARAPPARDPOLB | |
| SCHEMBL4728138 | 0.87 | PPARG (0.58) | PPARGPPARAPPARDPOLB | |
| SCHEMBL4726339 | 0.86 | PPARG (0.58) | PPARGPPARAPPARDPOLB | |
| SCHEMBL4729541 | 0.85 | PPARG (0.72) | PPARGPPARAPPARDPOLB | |
| SCHEMBL4731237 | 0.85 | PPARG (0.73) | PPARGPPARAPPARDPOLB | |
| SCHEMBL4731241 | 0.83 | PPARG (0.49) | PPARGPPARAPPARDPOLB | |
| SCHEMBL4726349 | 0.82 | PPARG (0.48) | PPARGPPARAPPARD | |
| SCHEMBL4728569 | 0.82 | PPARG (0.72) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423383-B1 | PYRIDINE SUBSTITUTED FURAN DERIVATIVES AS RAF KINASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2008-08-06 | — | — | EP | claimed |
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |