SCHEMBL4728134

SCHEMBL4728134

CCC(Oc1ccc(/C(=N\OCc2nc(-c3ccc(C)cc3)oc2C)c2ccccc2)cc1C)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARG P37231 15/20 0.58
PPARA Q07869 12/20 0.58
PPARD Q03181 4/20 0.58
TP53 P04637 3/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4728138 1.00 PPARG (0.58) PPARGPPARAPPARDTP53POLB
SCHEMBL4731237 0.89 PPARG (0.73) PPARGPPARAPPARDTP53POLB
SCHEMBL4726339 0.89 PPARG (0.58) PPARGPPARAPPARDTP53POLB
SCHEMBL4727907 0.88 PPARG (0.56) PPARGPPARAPPARDTP53POLB
SCHEMBL4727900 0.87 PPARG (0.53) PPARGPPARAPPARDPOLB
SCHEMBL4728569 0.87 PPARG (0.72) PPARGPPARAPPARD
SCHEMBL4728564 0.87 PPARG (0.72) PPARGPPARAPPARD
SCHEMBL4731275 0.85 PPARG (0.79) PPARGPPARAPPARDTP53POLB
SCHEMBL4731269 0.85 PPARG (0.79) PPARGPPARAPPARDTP53POLB
SCHEMBL4729121 0.84 PPARA (0.54) PPARGPPARAPPARDPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO claimed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed