Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.82 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.82 |
| ▸ | HPGD | P15428 | 5/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.78 |
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | RAB9A | P51151 | 3/20 | 0.78 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19322155 | 0.90 | KDM4E (1.00) | MAPTKDM4EMAPK1NPSR1HPGD | |
| SCHEMBL10753524 | 0.83 | HDAC6 (0.73) | MAPTKDM4EMAPK1NPSR1HPGD | |
| SCHEMBL4728174 | 0.83 | KDM4E (0.75) | MAPTKDM4EMAPK1NPSR1HPGD | |
| SCHEMBL6388717 | 0.82 | RAB9A (0.71) | MAPTKDM4EMAPK1HPGDSMN1; SMN2 | |
| SCHEMBL13325896 | 0.81 | ALDH1A3 (0.71) | KDM4EMAPK1HPGDSMN1; SMN2RAB9A | |
| Zolimidine SCHEMBL932657 | 0.79 | HDAC6 (1.00) | MAPTKDM4EMAPK1NPSR1HPGD | |
| Zolimidine SCHEMBL29405502 | 0.77 | HDAC6 (0.97) | MAPTKDM4EMAPK1NPSR1HPGD | |
| SCHEMBL4726872 | 0.76 | MAPT (0.72) | MAPTKDM4EMAPK1NPSR1HPGD | |
| SCHEMBL19322170 | 0.76 | KDM4E (0.63) | MAPTKDM4EMAPK1NPSR1HPGD | |
| SCHEMBL10754655 | 0.76 | HDAC6 (0.74) | MAPTKDM4EMAPK1NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029152-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |