SCHEMBL472803

SCHEMBL472803

OCc1sc(=S)sc1CO

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9966719 0.67
SCHEMBL13105905 0.57 MAPT (0.30) HSD17B10
SCHEMBL12220287 0.55 GPR35 (0.31) HSD17B10
SCHEMBL11339677 0.55 POLB (0.33)
SCHEMBL2376412 0.52
SCHEMBL3468019 0.52 HSD17B10 (0.50) CYP1A2CYP3A4CYP2C19HSD17B10
SCHEMBL10408804 0.50 KDM4E (0.31) CYP3A4
SCHEMBL10401255 0.50
SCHEMBL9185875 0.50
SCHEMBL29785816 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11681176-B2 Solar reflective and absorptive electrically-switchable film and glazing GAUZY LTD. (IL) 2023-06-20 US disclosed
US-8530673-B2 Tetrathiafulvalene derivative, and organic film and organic transistor using the same RICOH COMPANY, LTD. (JP) 2013-09-10 US disclosed
EP-2411378-B1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME RICOH CO LTD (JP) 2012-12-19 EP disclosed
EP-2411378-B1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME RICOH CO LTD (JP) 2012-12-19 EP disclosed
US-20120035364-A1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME RICOH COMPANY, LTD. (JP) 2012-02-09 US disclosed
US-20120035364-A1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME RICOH COMPANY, LTD. (JP) 2012-02-09 US disclosed
US-20120035364-A1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME RICOH COMPANY, LTD. (JP) 2012-02-09 US disclosed
EP-2411378-A1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME Ricoh Company, Ltd. (JP) 2012-02-01 EP disclosed
WO-2010110351-A1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME RICOH COMPANY, LTD. (JP) 2010-09-30 WO disclosed
WO-2010110351-A1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME RICOH COMPANY, LTD. (JP) 2010-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035364-A1 TETRATHIAFULVALENE DERIVATIVE, AND ORGANIC FILM AND ORGANIC TRANSISTOR USING THE SAME TCOF1, F12, F5 CYP1A2 467/4885CYP3A4 179/4885CYP2C19 906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.