Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.38 |
| ▸ | ELOC | Q15369 | 1/20 | 0.38 |
| ▸ | ELOB | Q15370 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25883876 | 0.91 | LMNA (0.41) | KDM4ESMN1; SMN2NPSR1LMNAKMT2A | |
| SCHEMBL30308402 | 0.91 | LMNA (0.41) | KDM4ESMN1; SMN2NPSR1LMNAKMT2A | |
| SCHEMBL11338074 | 0.86 | KDM4E (0.47) | KDM4ESMN1; SMN2NPSR1LMNAKMT2A | |
| SCHEMBL13214 | 0.86 | KDM4E (0.44) | KDM4ESMN1; SMN2NPSR1LMNAKMT2A | |
| SCHEMBL9522559 | 0.85 | KDM4E (0.44) | KDM4ESMN1; SMN2NPSR1LMNAKMT2A | |
| SCHEMBL14714 | 0.85 | PPARG (0.41) | KDM4ESMN1; SMN2KMT2AGAAHPGD | |
| SCHEMBL7554 | 0.83 | ALDH1A1 (0.41) | KDM4ENPSR1KMT2AGAAHPGD | |
| SCHEMBL30460538 | 0.83 | ALDH1A1 (0.41) | KDM4ENPSR1KMT2AGAAHPGD | |
| SCHEMBL24189203 | 0.81 | KDM4E (0.41) | KDM4ESMN1; SMN2NPSR1LMNAKMT2A | |
| SCHEMBL30308393 | 0.81 | KDM4E (0.41) | KDM4ESMN1; SMN2NPSR1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |