Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.45 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.44 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811950 | 0.84 | SMN1; SMN2 (0.57) | HPGDLMNAPTPN1GLRA1TAOK1 | |
| SCHEMBL7848012 | 0.83 | LMNA (0.50) | HPGDLMNAPTPN1GLRA1TAOK1 | |
| SCHEMBL262646 | 0.82 | MEN1 (0.63) | HPGDLMNAPTPN1GLRA1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL16143479 | 0.81 | MEN1 (0.61) | HPGDLMNAPTPN1GLRA1MRGPRX4 | |
| SCHEMBL4784102 | 0.81 | MAOB (0.59) | HPGDLMNAPTPN1GLRA1MRGPRX4 | |
| SCHEMBL14466872 | 0.80 | SMN1; SMN2 (0.62) | HPGDLMNAPTPN1GLRA1TAOK1 | |
| SCHEMBL262288 | 0.80 | MAPT (0.56) | HPGDLMNAPTPN1GLRA1TAOK1 | |
| SCHEMBL348412 | 0.80 | GLRA1 (0.68) | HPGDLMNAPTPN1GLRA1TAOK1 | |
| SCHEMBL12692634 | 0.80 | HPGD (0.47) | HPGDLMNAPTPN1GLRA1TAOK1 | |
| SCHEMBL12694523 | 0.80 | LMNA (0.47) | HPGDLMNAPTPN1GLRA1TAOK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052288-A1 | DITHIOLE COMPOUNDS AS COX INHIBITORS | NEURO THERAPEUTICS LIMITED (AU) | 2008-05-08 | — | — | WO | disclosed |