Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916872 | 0.90 | MAOB (0.52) | MAOBLMNAHPGDPTPN1SMN1; SMN2 | |
| SCHEMBL262646 | 0.89 | MEN1 (0.63) | LMNAHPGDPTPN1GLRA1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL16143479 | 0.87 | MEN1 (0.61) | LMNAHPGDPTPN1GLRA1MRGPRX4 | |
| SCHEMBL348412 | 0.86 | GLRA1 (0.68) | MAOBLMNAHPGDPTPN1ALDH1A1 | |
| SCHEMBL6811950 | 0.84 | SMN1; SMN2 (0.57) | MAOBLMNAHPGDPTPN1SMN1; SMN2 | |
| SCHEMBL12377619 | 0.84 | TDP1 (0.60) | LMNAHPGDPTPN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL17971071 | 0.84 | LMNA (0.75) | MAOBLMNAHPGDPTPN1SMN1; SMN2 | |
| SCHEMBL2343079 | 0.84 | MAOB (0.59) | MAOBLMNAHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL14466872 | 0.83 | SMN1; SMN2 (0.62) | MAOBLMNAHPGDPTPN1SMN1; SMN2 | |
| SCHEMBL262288 | 0.83 | MAPT (0.56) | LMNAHPGDPTPN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052288-A1 | DITHIOLE COMPOUNDS AS COX INHIBITORS | NEURO THERAPEUTICS LIMITED (AU) | 2008-05-08 | — | — | WO | disclosed |
| CN-1151130-C | Neuroprotective 3- (piperidinyl-1) -chroman-4, 7-diol and 1- (4-hydroxyphenyl) -2- (piperidinyl-1) alkanol derivatives | ������ҩ������˾ | 2004-05-26 | — | — | CN | disclosed |
| CN-1155279-A | Neuroprotective 3-(piperidinyl-1)-chroman-4,7,-diol and 1-(4-hydrophenyl)-2-(piperidinyl-1)-alkane alcohol | PFIZER (US) | 1997-07-23 | — | — | CN | disclosed |