Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 10/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | PTPRF | P10586 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12996512 | 0.81 | ALOX5 (0.71) | ALOX5GGPS1PTGES2PRKDCATM | |
| SCHEMBL15855421 | 0.79 | ALOX5 (0.69) | ALOX5GGPS1PTGES2PRKDCATM | |
| SCHEMBL12996525 | 0.79 | ALOX5 (0.69) | ALOX5GGPS1PTGES2PRKDCATM | |
| SCHEMBL431478 | 0.78 | ALOX5 (0.67) | ALOX5GGPS1PTGES2PRKDCATM | |
| SCHEMBL12996518 | 0.76 | ALOX5 (0.65) | ALOX5GGPS1PTGES2PRKDCATM | |
| SCHEMBL29892450 | 0.76 | ALOX5 (0.65) | ALOX5GGPS1PTGES2PRKDCATM | |
| SCHEMBL18698089 | 0.76 | ALOX5 (0.65) | ALOX5GGPS1PTGES2PRKDCATM | |
| SCHEMBL30120167 | 0.76 | ALOX5 (0.68) | ALOX5GGPS1PTGES2PRKDCATM | |
| SCHEMBL1687979 | 0.76 | ALOX5 (0.68) | ALOX5GGPS1PTGES2PRKDCATM | |
| SCHEMBL125790 | 0.75 | ALOX5 (0.63) | ALOX5GGPS1PTGES2PRKDCATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033934-A1 | SUBSTITUTED HETEROARYL CARBOXYLIC ACID DERIVATIVES AS PTB-1B INHIBITORS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2008-03-20 | — | — | WO | disclosed |