Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CALML3 | P27482 | 1/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14261405 | 0.86 | ALDH1A1 (0.54) | KDM4EHSD17B10ALDH1A1MAOAMAOB | |
| SCHEMBL4783416 | 0.85 | HSD17B10 (0.53) | KDM4EHSD17B10ALDH1A1HPGDF10 | |
| SCHEMBL4728133 | 0.83 | SCD (0.53) | KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL4778897 | 0.83 | SCD (0.53) | KDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL14261606 | 0.81 | F10 (0.47) | F10MAOAMAOBCALML3 | |
| SCHEMBL14261417 | 0.78 | CALML3 (0.52) | ALDH1A1HPGDF10MAOAMAOB | |
| SCHEMBL14261644 | 0.78 | CALML3 (0.52) | ALDH1A1HPGDF10MAOAMAOB | |
| SCHEMBL4783498 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1HPGDMAOAMAOB | |
| SCHEMBL14261642 | 0.77 | CALML3 (0.43) | KDM4EALDH1A1F10MAOAMAOB | |
| SCHEMBL4727825 | 0.77 | CALML3 (0.43) | KDM4EALDH1A1F10MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029266-A1 | STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-03-13 | — | — | WO | claimed |