Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CALML3 | P27482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14261404 | 1.00 | KDM4E (0.49) | KDM4ELMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL4778897 | 0.83 | SCD (0.53) | KDM4ELMNASMN1; SMN2HTT | |
| SCHEMBL4728133 | 0.83 | SCD (0.53) | KDM4ELMNASMN1; SMN2HTT | |
| SCHEMBL4727825 | 0.81 | CALML3 (0.43) | KDM4ELMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14261642 | 0.81 | CALML3 (0.43) | KDM4ELMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL4783416 | 0.81 | HSD17B10 (0.53) | KDM4ELMNAALDH1A1CALML3MEN1 | |
| SCHEMBL14261405 | 0.79 | ALDH1A1 (0.54) | KDM4ELMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL14261606 | 0.79 | F10 (0.47) | CALML3CYP2C9CYP2C19MAOAMAOB | |
| SCHEMBL14261415 | 0.78 | SCD (0.53) | KDM4ELMNASMN1; SMN2HTT | |
| SCHEMBL4728322 | 0.77 | GAA (0.54) | KDM4ELMNASMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029266-A1 | STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-03-13 | — | — | WO | claimed |
| WO-2008029266-A1 | STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-03-13 | — | — | WO | disclosed |