Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.60 |
| ▸ | RORC | P51449 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728967 | 1.00 | KDM4E (0.64) | KDM4EMAPTMEN1LMNAKMT2A | |
| SCHEMBL4728393 | 0.88 | KDM4E (0.83) | KDM4EMAPTMEN1LMNAKMT2A | |
| SCHEMBL4728399 | 0.88 | KDM4E (0.83) | KDM4EMAPTMEN1LMNAKMT2A | |
| SCHEMBL4730104 | 0.87 | NPY5R (0.67) | KDM4EMAPTMEN1LMNAKMT2A | |
| SCHEMBL4729244 | 0.83 | NPSR1 (0.76) | KDM4EMAPTMEN1LMNAKMT2A | |
| SCHEMBL4728698 | 0.83 | MAPT (0.64) | KDM4EMAPTMEN1LMNAKMT2A | |
| SCHEMBL4728749 | 0.83 | NPY5R (0.78) | KDM4EMAPTMEN1LMNAKMT2A | |
| SCHEMBL4730385 | 0.82 | HDAC6 (0.59) | KDM4EMAPTMEN1LMNAKMT2A | |
| SCHEMBL21889882 | 0.82 | P2RX4 (0.58) | KDM4EMAPTMEN1LMNAKMT2A | |
| SCHEMBL4725134 | 0.80 | MAPT (0.77) | KDM4EMAPTMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |