Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726479 | 0.92 | KMT2A (0.67) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL4895642 | 0.91 | KMT2A (0.51) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL4728400 | 0.84 | KMT2A (0.65) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL7979591 | 0.81 | KDM4E (0.72) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL14880207 | 0.80 | KMT2A (0.54) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL4727890 | 0.79 | KDM4E (0.56) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL8527482 | 0.79 | HTR1B (0.69) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL5808503 | 0.79 | KMT2A (0.61) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL20601994 | 0.79 | SIRT1 (0.58) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL22134580 | 0.79 | KMT2A (0.51) | KMT2AMEN1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |