Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | FADS1 | O60427 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781584 | 0.84 | P2RX7 (0.41) | CRBNALDH1A1KDM4ENPC1HSD17B10 | |
| SCHEMBL30583795 | 0.74 | ALDH1A1 (0.43) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL1150620 | 0.72 | KDM4E (0.70) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL3709144 | 0.72 | KDM4E (0.70) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL2060435 | 0.71 | CRBN (0.56) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| Water SCHEMBL28110279 | 0.70 | CRBN (0.55) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL5668549 | 0.70 | ALDH1A1 (0.53) | ALDH1A1KDM4ENPC1RAB9AGAA | |
| SCHEMBL9921278 | 0.69 | KDM4E (0.60) | ALDH1A1KDM4ENPC1RAB9AGAA | |
| SCHEMBL31267432 | 0.69 | ALDH1A1 (0.59) | CRBNALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL22720116 | 0.69 | ALDH1A1 (0.66) | CRBNALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031548-A1 | PROCESS FOR THE PREPARATION OF ANTHRANILAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008031549-A1 | PROCESS FOR THE PREPARATION OF ANTHRANILAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-20 | — | — | WO | disclosed |