SCHEMBL4728490

SCHEMBL4728490

CCCCCO[Si](O)(OCCCCC)OCCCCC

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41
CA9 Q16790 4/20 0.41
CA12 O43570 3/20 0.41
THRB P10828 2/20 0.41
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.41
LPAR3 Q9UBY5 6/20 0.39
LPAR2 Q9HBW0 5/20 0.39
LPAR1 Q92633 2/20 0.39
NAAA Q02083 1/20 0.39
CES2 O00748 1/20 0.38
GBA1 P04062 1/20 0.38
TSHR P16473 1/20 0.37
EPHX1 P07099 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10438599 0.97 THRB (0.44) CA1CA2CA9CA12THRB
SCHEMBL8955296 0.97 THRB (0.44) CA1CA2CA9CA12THRB
SCHEMBL3790659 0.92 TSHR (0.42) CA1CA2CA9CA12THRB
SCHEMBL27606111 0.86 CA1 (0.39) CA1CA2CA9CA12THRB
SCHEMBL28753472 0.84 THRB (0.43) CA1CA2CA9CA12THRB
SCHEMBL28041986 0.84 THRB (0.43) CA1CA2CA9CA12THRB
SCHEMBL4808126 0.84 THRB (0.43) CA1CA2CA9CA12THRB
SCHEMBL28970583 0.84 THRB (0.43) CA1CA2CA9CA12THRB
SCHEMBL75709 0.83 CA1 (0.41) CA1CA2CA9CA12THRB
SCHEMBL25191483 0.81 THRB (0.44) CA1CA2CA9CA12THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008042032-A1 APPARATUS AND METHOD FOR DELIVERING UNIFORM FLUID FLOW IN A CHEMICAL DEPOSITION SYSTEM NOVELLUS SYSTEMS, INC. (US) 2008-04-10 WO disclosed
US-20080081114-A1 Apparatus and method for delivering uniform fluid flow in a chemical deposition system NOVELLUS SYSTEMS, INC. 2008-04-03 US disclosed
EP-0123060-B1 ULTRAPURE CRYSTALLINE SILICA POLYMORPHS AND PROCESS FOR THE PREPARATION THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-04 EP disclosed
EP-0123060-A1 Ultrapure crystalline silica polymorphs and process for the preparation thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-31 EP disclosed