SCHEMBL8955296

SCHEMBL8955296

CCCCCCO[Si](O)(OCCCCCC)OCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HTT P42858 1/20 0.44
MAPT P10636 1/20 0.44
LPAR3 Q9UBY5 6/20 0.43
LPAR2 Q9HBW0 5/20 0.43
LPAR1 Q92633 2/20 0.43
NAAA Q02083 1/20 0.43
TSHR P16473 1/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41
CES2 O00748 1/20 0.41
GBA1 P04062 1/20 0.41
EPHX1 P07099 1/20 0.40
LMNA P02545 2/20 0.39
ALDH1A1 P00352 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10438599 1.00 THRB (0.44) THRBMEN1KMT2AHTTMAPT
SCHEMBL4728490 0.97 CA1 (0.41) THRBMEN1KMT2AHTTMAPT
SCHEMBL3790659 0.89 TSHR (0.42) THRBMEN1KMT2AHTTMAPT
SCHEMBL28753472 0.87 THRB (0.43) THRBMEN1KMT2AHTTMAPT
SCHEMBL28970583 0.87 THRB (0.43) THRBMEN1KMT2AHTTMAPT
SCHEMBL28041986 0.87 THRB (0.43) THRBMEN1KMT2AHTTMAPT
SCHEMBL4808126 0.87 THRB (0.43) THRBMEN1KMT2AHTTMAPT
SCHEMBL25191483 0.84 THRB (0.44) THRBMEN1KMT2AHTTMAPT
SCHEMBL1276157 0.84 THRB (0.44) THRBMEN1KMT2AHTTMAPT
SCHEMBL1157411 0.84 THRB (0.44) THRBMEN1KMT2AHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484685-A Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof HITACHI, LTD. (JP) 1996-01-16 US disclosed
EP-0366440-B1 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof HITACHI CHEMICAL CO LTD (JP) 1994-06-08 EP disclosed
EP-0366440-A2 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof Hitachi Chemical Co., Ltd. (JP) 1990-05-02 EP disclosed