Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.67 |
| ▸ | RORC | P51449 | 6/20 | 0.61 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727562 | 0.93 | NPY5R (0.65) | NPY5RRORCPTGDR2CNR2MAPT | |
| SCHEMBL4726986 | 0.89 | NPY5R (0.71) | NPY5RRORCCNR2MAPTKDM4E | |
| SCHEMBL4727519 | 0.87 | NPY5R (0.83) | NPY5RRORCCNR2MAPTKDM4E | |
| SCHEMBL4728750 | 0.86 | NPY5R (0.62) | NPY5RRORCCNR2MAPTKDM4E | |
| SCHEMBL4727844 | 0.85 | RORC (0.77) | NPY5RRORCMAPT | |
| SCHEMBL4727066 | 0.82 | NPY5R (0.60) | NPY5RRORCCNR2MAPTKDM4E | |
| SCHEMBL4727906 | 0.82 | PTGER4 (0.67) | NPY5RRORCMAPTKDM4ELMNA | |
| SCHEMBL30062001 | 0.82 | PTGER4 (0.67) | NPY5RRORCMAPTKDM4ELMNA | |
| SCHEMBL4726955 | 0.81 | PTGDR2 (0.77) | NPY5RRORCPTGDR2MAPTKDM4E | |
| SCHEMBL7976855 | 0.81 | NPY5R (1.00) | NPY5RRORCCNR2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |