Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 1.00 |
| ▸ | CNR2 | P34972 | 1/20 | 0.62 |
| ▸ | RORC | P51449 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727519 | 0.91 | NPY5R (0.83) | NPY5RCNR2RORCMAPTRAB9A | |
| SCHEMBL4726986 | 0.84 | NPY5R (0.71) | NPY5RCNR2RORCMAPTMEN1 | |
| SCHEMBL4728500 | 0.81 | NPY5R (0.67) | NPY5RCNR2RORCMAPTMEN1 | |
| SCHEMBL4727844 | 0.80 | RORC (0.77) | NPY5RRORCMAPT | |
| SCHEMBL4727562 | 0.79 | NPY5R (0.65) | NPY5RCNR2RORCMAPTMEN1 | |
| SCHEMBL4727906 | 0.77 | PTGER4 (0.67) | NPY5RRORCMAPTMEN1ALDH1A1 | |
| SCHEMBL30062001 | 0.77 | PTGER4 (0.67) | NPY5RRORCMAPTMEN1ALDH1A1 | |
| SCHEMBL4728750 | 0.77 | NPY5R (0.62) | NPY5RCNR2RORCMAPTMEN1 | |
| SCHEMBL600414 | 0.76 | CNR2 (1.00) | NPY5RCNR2RORCMAPT | |
| SCHEMBL16345038 | 0.76 | ROCK2 (0.67) | NPY5RMAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |