Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782932 | 0.80 | ALDH1A1 (0.52) | KDM1AMAOAMAOB | |
| SCHEMBL22961935 | 0.76 | HTR7 (0.47) | SLC6A4MEN1KMT2AHTR2CHTR2B | |
| SCHEMBL90448 | 0.76 | MEN1 (0.57) | SLC6A4MEN1KMT2ASMN1; SMN2REN | |
| SCHEMBL89815 | 0.76 | MEN1 (0.54) | SLC6A4MEN1KMT2ASMN1; SMN2REN | |
| Hydrochloric Acid SCHEMBL2806174 | 0.75 | MEN1 (0.53) | SLC6A4MEN1KMT2ASMN1; SMN2REN | |
| SCHEMBL2807945 | 0.73 | NPC1 (0.51) | MEN1KMT2ASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL13185202 | 0.71 | BIRC5 (0.46) | SLC6A4MEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL8316562 | 0.71 | KMT2A (0.62) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2085628 | 0.70 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1057005 | 0.70 | NPC1 (0.47) | SLC6A4MEN1KMT2ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008044144-A2 | CHIRAL TETRA-HYDRO BETA-CARBOLIC DERIVATIVES AND APPLICATIONS THEREOF AS ANTIPARASITIC COMPOUNDS | UNIVERSITE DE LILLE 2, UNIVERSITÉ DU DROIT ET DE LA SANTÉ (FR) | 2008-04-17 | — | — | WO | disclosed |