SCHEMBL4728608

SCHEMBL4728608

CCC(Oc1ccc(CC(C)=NOCc2nc(-c3ccc(C)cc3)oc2C)cc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.51
PPARA Q07869 18/20 0.51
PPARD Q03181 3/20 0.49
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4728605 0.85 PPARG (0.52) PPARGPPARAPPARDPOLB
SCHEMBL4728895 0.84 PPARG (0.61) PPARGPPARAPPARDPOLB
SCHEMBL4728610 0.83 PPARA (0.49) PPARGPPARAPPARDPOLB
SCHEMBL4726343 0.80 PPARG (0.53) PPARGPPARAPPARDPOLB
SCHEMBL4728538 0.79 PPARG (0.56) PPARGPPARAPPARD
SCHEMBL4730159 0.79 PPARG (0.56) PPARGPPARAPPARD
SCHEMBL4727900 0.78 PPARG (0.53) PPARGPPARAPPARDPOLB
SCHEMBL4731237 0.78 PPARG (0.73) PPARGPPARAPPARDPOLB
SCHEMBL4727907 0.77 PPARG (0.56) PPARGPPARAPPARDPOLB
SCHEMBL4728540 0.77 PPARG (0.56) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO claimed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed