Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 13/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 13/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 13/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1846177 | 0.84 | CYP2D6 (0.39) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL1846153 | 0.84 | CYP2D6 (0.39) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL14291856 | 0.83 | CHRM3 (0.39) | ALDH1A1CHRM3CHRM2CHRM1CHRM4 | |
| SCHEMBL14291318 | 0.81 | ACHE (0.40) | POLBALDH1A1CHRM3CHRM2CHRM1 | |
| SCHEMBL4793046 | 0.80 | CHRM3 (0.43) | POLBALDH1A1CHRM3CHRM2CHRM1 | |
| SCHEMBL1109790 | 0.76 | CHRM3 (0.41) | POLBALDH1A1CHRM3CHRM2CHRM1 | |
| SCHEMBL4777456 | 0.76 | POLB (0.41) | POLBALDH1A1CHRM3CHRM2CHRM1 | |
| SCHEMBL4739830 | 0.76 | CHRM3 (0.41) | POLBALDH1A1CHRM3CHRM2CHRM1 | |
| SCHEMBL4727371 | 0.76 | CHRM3 (0.43) | POLBALDH1A1CHRM3CHRM2CHRM1 | |
| SCHEMBL1109782 | 0.76 | CHRM3 (0.41) | POLBALDH1A1CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |