Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 1.00 |
| ▸ | GFER | P55789 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | MIF | P14174 | 1/20 | 1.00 |
| ▸ | CLK1 | P49759 | 1/20 | 0.69 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 10/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | PKM | P14618 | 5/20 | 0.62 |
| ▸ | CASP6 | P55212 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340215 | 0.87 | RAB9A (0.76) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL10242020 | 0.87 | RAB9A (0.76) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL12848509 | 0.83 | RAB9A (0.76) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL13325909 | 0.83 | RAB9A (0.83) | RAB9AGFERKMT2AGAAMEN1 | |
| Bromide SCHEMBL6525392 | 0.82 | RAB9A (0.79) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL3304334 | 0.82 | RAB9A (0.97) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL13325938 | 0.81 | RAB9A (0.80) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL13131131 | 0.81 | RAB9A (0.69) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL13325743 | 0.81 | RAB9A (0.68) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL29614084 | 0.81 | RAB9A (0.68) | RAB9AGFERKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029152-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |