Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.76 |
| ▸ | GFER | P55789 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | MIF | P14174 | 1/20 | 0.76 |
| ▸ | NPC1 | O15118 | 10/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | CLK1 | P49759 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10242020 | 0.89 | RAB9A (0.76) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL6875395 | 0.87 | RAB9A (0.64) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL4728739 | 0.87 | RAB9A (1.00) | RAB9AGFERKMT2AGAAMEN1 | |
| Hydrochloric Acid SCHEMBL6392312 | 0.85 | RAB9A (0.62) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL20022681 | 0.82 | NPC1 (0.78) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL5305222 | 0.81 | RAB9A (0.61) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL8342931 | 0.81 | RAB9A (0.78) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL12848509 | 0.80 | RAB9A (0.76) | RAB9AGFERKMT2AGAAMEN1 | |
| SCHEMBL13325909 | 0.79 | RAB9A (0.83) | RAB9AGFERKMT2AGAAMEN1 | |
| Bromide SCHEMBL6525392 | 0.79 | RAB9A (0.79) | RAB9AGFERKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024074-A2 | FUSED HETEROBICYCLO SUBSTITUTED PHENYL METABOTROPIC GLUTAMATE-5 MODULATORS | MERCK & CO., INC. (US) | 2004-03-25 | — | — | WO | disclosed |