Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010574 | 0.89 | ALDH1A1 (0.70) | ALDH1A1HSD17B10RECQLNPSR1HPGD | |
| SCHEMBL14494978 | 0.85 | APEX1 (0.55) | ALDH1A1HSD17B10RECQLNPSR1APEX1 | |
| SCHEMBL1250706 | 0.84 | ANPEP (0.66) | ALDH1A1HSD17B10RECQLNPSR1HPGD | |
| SCHEMBL10518628 | 0.84 | NPSR1 (0.67) | ALDH1A1HSD17B10RECQLNPSR1HPGD | |
| SCHEMBL30758617 | 0.78 | KMT2A (0.62) | ALDH1A1TDP1POLBKMT2AMEN1 | |
| SCHEMBL29168855 | 0.78 | KMT2A (0.62) | ALDH1A1TDP1POLBKMT2AMEN1 | |
| SCHEMBL4230873 | 0.78 | APEX1 (0.86) | ALDH1A1HSD17B10RECQLNPSR1HPGD | |
| SCHEMBL8066752 | 0.78 | ALDH1A1 (0.72) | ALDH1A1HSD17B10RECQLNPSR1HPGD | |
| SCHEMBL17946428 | 0.78 | APEX1 (0.68) | ALDH1A1HSD17B10RECQLNPSR1HPGD | |
| SCHEMBL8851298 | 0.78 | APEX1 (0.67) | ALDH1A1HSD17B10RECQLNPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029168-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |