SCHEMBL8066752

SCHEMBL8066752

O=C(O)c1ccc2c(c1)C(=O)N(c1ccccc1O)C2=O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.72
RECQL P46063 1/20 0.64
HSD17B10 Q99714 1/20 0.64
APEX1 P27695 1/20 0.63
HPGD P15428 2/20 0.62
TDP1 Q9NUW8 1/20 0.62
POLB P06746 4/20 0.62
KMT2A Q03164 4/20 0.62
DNM2 P50570 1/20 0.61
MEN1 O00255 3/20 0.57
GFER P55789 1/20 0.57
TSHR P16473 1/20 0.56
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA9 Q16790 3/20 0.53
CA4 P22748 2/20 0.53
NPSR1 Q6W5P4 1/20 0.52
ENPP2 Q13822 1/20 0.52
CA12 O43570 1/20 0.51
SCN2A Q99250 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17946433 0.89 APEX1 (0.69) ALDH1A1RECQLHSD17B10APEX1HPGD
SCHEMBL4230873 0.85 APEX1 (0.86) ALDH1A1RECQLHSD17B10APEX1HPGD
SCHEMBL21857580 0.85 ALDH1A1 (0.71) ALDH1A1RECQLHSD17B10APEX1HPGD
SCHEMBL5008605 0.84 ALDH1A1 (0.70) ALDH1A1RECQLHSD17B10APEX1HPGD
SCHEMBL5010574 0.84 ALDH1A1 (0.70) ALDH1A1RECQLHSD17B10APEX1HPGD
SCHEMBL5010947 0.84 ALDH1A1 (0.70) ALDH1A1RECQLHSD17B10APEX1HPGD
SCHEMBL9752402 0.82 ALDH1A1 (0.68) ALDH1A1RECQLHSD17B10APEX1HPGD
SCHEMBL8851298 0.81 APEX1 (0.67) ALDH1A1RECQLHSD17B10APEX1HPGD
SCHEMBL14586374 0.81 ENPP2 (0.74) ALDH1A1RECQLHSD17B10APEX1HPGD
SCHEMBL1618163 0.81 KMT2A (0.76) ALDH1A1RECQLHSD17B10POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62290752-A None JP disclosed
JP-2000017048-A EPOXY COMPOUND HAVING IMIDE SKELETON AND CURABLE EPOXY RESIN COMPOSITION CONTAINING THE SAME NIPPON KAYAKU CO LTD 2000-01-18 JP disclosed
JP-S62290752-A RESIN COMPOSITION IDEMITSU KOSAN CO LTD 1987-12-17 JP disclosed