Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | GOT1 | P17174 | 2/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725640 | 0.91 | MAPT (0.49) | MAPTBACE1GPR119PDK2ALDH1A1 | |
| SCHEMBL5373904 | 0.86 | BACE1 (0.51) | MAPTBACE1GPR119MTNR1BPDK2 | |
| SCHEMBL5372246 | 0.85 | HTR5A (0.55) | MAPTBACE1GPR119MTNR1BPDK2 | |
| SCHEMBL31185603 | 0.85 | HTR5A (0.55) | MAPTBACE1GPR119MTNR1BPDK2 | |
| SCHEMBL5375431 | 0.84 | BACE1 (0.51) | MAPTBACE1GPR119MTNR1BHTR1A | |
| SCHEMBL6308917 | 0.84 | BACE1 (0.51) | MAPTBACE1GPR119MTNR1BPDK2 | |
| SCHEMBL4558301 | 0.83 | BACE1 (0.59) | MAPTBACE1GPR119HTR1AHTR1D | |
| SCHEMBL5379402 | 0.83 | BACE1 (0.50) | MAPTBACE1GPR119MTNR1BPDK2 | |
| SCHEMBL5363589 | 0.83 | MTNR1B (0.69) | MAPTBACE1MTNR1BHTR1AHTR1D | |
| SCHEMBL5366413 | 0.82 | BACE1 (0.49) | MAPTBACE1GPR119MTNR1BPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020306-A2 | ISOINDOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | disclosed |