Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4727330 | 0.98 | MAPT (0.57) | MAPTTP53LMNATHRBKDR | |
| SCHEMBL2966951 | 0.88 | MAPT (0.48) | MAPTTP53LMNATHRBKDR | |
| Hydrochloric Acid SCHEMBL6220144 | 0.87 | MAPT (0.47) | MAPTTP53LMNATHRBKDR | |
| SCHEMBL2968890 | 0.83 | MAPT (0.50) | MAPTTP53LMNATHRBKDR | |
| SCHEMBL23010594 | 0.82 | MAPT (0.58) | MAPTTP53LMNATHRBHTR1A | |
| SCHEMBL8915792 | 0.82 | MAPT (0.58) | MAPTTP53LMNATHRBHTR1A | |
| Maleic Acid SCHEMBL3901903 | 0.78 | TP53 (0.43) | MAPTTP53LMNATHRBKDR | |
| Fumaric Acid SCHEMBL3901905 | 0.78 | TP53 (0.43) | MAPTTP53LMNATHRBKDR | |
| SCHEMBL7815883 | 0.78 | HTR6 (0.53) | MAPTTP53LMNAHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL6220118 | 0.76 | KDM4E (0.54) | MAPTTP53LMNAHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020306-A2 | ISOINDOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | disclosed |