Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.58 |
| ▸ | TP53 | P04637 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729065 | 0.82 | MAPT (0.58) | MAPTTP53LMNATHRBHTR1A | |
| Hydrochloric Acid SCHEMBL4727330 | 0.81 | MAPT (0.57) | MAPTTP53LMNATHRBHTR1A | |
| SCHEMBL6986929 | 0.74 | MAPT (0.51) | MAPTTP53LMNATHRBHTR1A | |
| SCHEMBL1447764 | 0.72 | ALDH1A1 (0.43) | MAPTLMNAHTR1A | |
| SCHEMBL2966951 | 0.70 | MAPT (0.48) | MAPTTP53LMNATHRBHTR1A | |
| SCHEMBL8916927 | 0.70 | PTPN1 (0.40) | MAPTTP53LMNAHTR1A | |
| SCHEMBL8916889 | 0.70 | SMN1; SMN2 (0.36) | MAPTTP53LMNATHRBUSP2 | |
| SCHEMBL4142914 | 0.69 | DRD2 (0.45) | MAPTLMNATHRB | |
| Hydrochloric Acid SCHEMBL6220144 | 0.69 | MAPT (0.47) | MAPTTP53LMNATHRBHTR1A | |
| SCHEMBL13898747 | 0.67 | DRD4 (0.47) | MAPTTP53LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |