Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 7/20 | 0.40 |
| ▸ | BRAF | P15056 | 7/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.40 |
| ▸ | FRK | P42685 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728099 | 0.90 | RAF1 (0.41) | IKBKBRAF1BRAFMAPK14EPHA3 | |
| SCHEMBL4730519 | 0.86 | ABCG2 (0.45) | ABCG2KDM4EALDH1A1 | |
| SCHEMBL4729072 | 0.85 | RAF1 (0.43) | RAF1BRAFEGLN1 | |
| SCHEMBL4725920 | 0.83 | EGLN1 (0.48) | MAPK14EGLN1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4727468 | 0.83 | MAPK14 (0.47) | RAF1BRAFMAPK14EPHA3FRK | |
| SCHEMBL4730006 | 0.82 | RAF1 (0.43) | RAF1BRAF | |
| SCHEMBL4726798 | 0.82 | RAF1 (0.42) | RAF1BRAF | |
| SCHEMBL4880516 | 0.82 | RAF1 (0.52) | IKBKBHSD17B10RAF1BRAFMAPK14 | |
| SCHEMBL4727842 | 0.81 | RAF1 (0.45) | RAF1BRAF | |
| SCHEMBL14293640 | 0.81 | RAF1 (0.51) | IKBKBHSD17B10RAF1BRAFMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |