Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456634 | 0.81 | CYP1A2 (0.67) | CYP1A2LOXL2NCF1KDM4EALDH1A1 | |
| SCHEMBL607974 | 0.81 | LOXL2 (0.51) | CYP1A2LOXL2NCF1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3805296 | 0.80 | CYP1A2 (0.65) | CYP1A2LOXL2NCF1KDM4EALDH1A1 | |
| SCHEMBL28001770 | 0.79 | LOXL2 (0.58) | CYP1A2LOXL2NCF1KDM4EALDH1A1 | |
| SCHEMBL31599195 | 0.78 | LOXL2 (0.67) | CYP1A2LOXL2NCF1KDM4EALDH1A1 | |
| SCHEMBL334360 | 0.78 | LOXL2 (0.67) | CYP1A2LOXL2NCF1KDM4EALDH1A1 | |
| SCHEMBL29987166 | 0.77 | CYP1A2 (0.61) | CYP1A2LOXL2NCF1KDM4EALDH1A1 | |
| SCHEMBL5239658 | 0.77 | CYP1A2 (0.61) | CYP1A2LOXL2NCF1KDM4EALDH1A1 | |
| SCHEMBL3775943 | 0.76 | CYP1A2 (0.60) | CYP1A2LOXL2NCF1KDM4EALDH1A1 | |
| SCHEMBL5508700 | 0.76 | CYP1A2 (0.60) | CYP1A2LOXL2NCF1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598651-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND ASSOCIATED WITH BACTERIAL INFECTION | Sanofi-Aventis Deutschland GmbH (DE) | 2013-06-05 | — | — | EP | disclosed |
| US-20130123360-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND ASSOCIATED WITH BACTERIAL INFECTION | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2013-05-16 | — | — | US | disclosed |
| WO-2012013621-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND ASSOCIATED WITH BACTERIAL INFECTION | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2012-02-02 | — | — | WO | disclosed |
| EP-2412819-A1 | Methods and uses relating to the identification of compound associated with bacterial infection | Sanofi-Aventis Deutschland GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |