Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727503 | 0.93 | SCARB1 (0.53) | SCARB1CNR2MAPTSMN1; SMN2LMNA | |
| SCHEMBL4727510 | 0.78 | SCARB1 (0.53) | SCARB1CNR2LMNAHPGDALDH1A1 | |
| SCHEMBL2056260 | 0.78 | CREBBP (0.51) | MAPTSMN1; SMN2LMNAKMT2ACREBBP | |
| SCHEMBL19559314 | 0.77 | MAPT (0.61) | SCARB1CNR2MAPTSMN1; SMN2LMNA | |
| SCHEMBL2802562 | 0.77 | CREBBP (0.48) | MAPTSMN1; SMN2LMNAKMT2ACREBBP | |
| SCHEMBL7163305 | 0.77 | HDAC1 (0.57) | MAPTSMN1; SMN2CREBBPHPGDALDH1A1 | |
| SCHEMBL7178691 | 0.76 | AKR1C3 (0.49) | MAPTSMN1; SMN2CREBBPHPGDALDH1A1 | |
| SCHEMBL4725248 | 0.76 | SCARB1 (0.52) | SCARB1CNR2MAPTLMNAPSEN1 | |
| SCHEMBL2875809 | 0.76 | SCARB1 (0.49) | SCARB1CNR2NPSR1PSEN1PSEN2 | |
| SCHEMBL3932512 | 0.75 | CNR2 (0.59) | SCARB1CNR2KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |