SCHEMBL2875809

SCHEMBL2875809

COC(=O)c1cc(OCCCCn2c3ccccc3c3ccccc32)c(OCCCCn2c3ccccc3c3ccccc32)c(OCCCCn2c3ccccc3c3ccccc32)c1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SCARB1 Q8WTV0 1/20 0.49
PSEN1 P49768 7/20 0.47
PSEN2 P49810 7/20 0.47
APH1B Q8WW43 7/20 0.47
NCSTN Q92542 7/20 0.47
APH1A Q96BI3 7/20 0.47
PSENEN Q9NZ42 7/20 0.47
HDAC1 Q13547 3/20 0.46
HDAC6 Q9UBN7 3/20 0.46
FABP4 P15090 2/20 0.46
FABP5 Q01469 2/20 0.46
CNR2 P34972 3/20 0.45
KDM4E B2RXH2 2/20 0.44
MAPK1 P28482 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2872778 0.89 PSEN1 (0.43) SCARB1PSEN1PSEN2APH1BNCSTN
SCHEMBL350674 0.85 PSEN1 (0.52) SCARB1PSEN1PSEN2APH1BNCSTN
SCHEMBL4725248 0.81 SCARB1 (0.52) SCARB1PSEN1PSEN2APH1BNCSTN
SCHEMBL4155967 0.81 MAPT (0.59) SCARB1PSEN1PSEN2APH1BNCSTN
SCHEMBL4727503 0.80 SCARB1 (0.53) SCARB1PSEN1PSEN2APH1BNCSTN
SCHEMBL4151119 0.80 PSEN1 (0.47) SCARB1PSEN1PSEN2APH1BNCSTN
SCHEMBL2875400 0.79 PSEN1 (0.53) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL19559314 0.78 MAPT (0.61) SCARB1PSEN1PSEN2APH1BNCSTN
SCHEMBL4729148 0.76 SCARB1 (0.47) SCARB1PSEN1PSEN2APH1BNCSTN
SCHEMBL3932512 0.76 CNR2 (0.59) SCARB1PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420231-B2 Iridium phosphorescent dendrimer, method of preparing the same and electroluminescent device including the iridium phosphorescent dendrimer SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-04-16 US disclosed
US-20100084970-A1 IRIDIUM PHOSPHORESCENT DENDRIMER, METHOD OF PREPARING THE SAME AND ELECTROLUMINESCENT DEVICE INCLUDING THE IRIDIUM PHOSPHORESCENT DENDRIMER SAMSUNG ELECTRONICS CO., LTD (KR) 2010-04-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100084970-A1 IRIDIUM PHOSPHORESCENT DENDRIMER, METHOD OF PREPARING THE SAME AND ELECTROLUMINESCENT DEVICE INCLUDING THE IRIDIUM PHOSPHORESCENT DENDRIMER DNM1, FIS1, DCUN1D1 SCARB1 3453/4885PSEN1 3218/4885PSEN2 4384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.