Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.52 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.50 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350674 | 0.94 | PSEN1 (0.52) | SCARB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19559314 | 0.88 | MAPT (0.61) | SCARB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4151119 | 0.87 | PSEN1 (0.47) | SCARB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4155967 | 0.85 | MAPT (0.59) | SCARB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4725252 | 0.83 | CNR2 (0.53) | SCARB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2875809 | 0.81 | SCARB1 (0.49) | SCARB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3932512 | 0.81 | CNR2 (0.59) | SCARB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2872778 | 0.81 | PSEN1 (0.43) | SCARB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4727503 | 0.81 | SCARB1 (0.53) | SCARB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13011578 | 0.79 | TSHR (0.56) | SCARB1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |