Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13180066 | 1.00 | TDP1 (0.38) | TDP1ALDH1A1TSHR | |
| SCHEMBL4729241 | 1.00 | TDP1 (0.38) | TDP1ALDH1A1TSHR | |
| SCHEMBL870003 | 0.91 | — | — | |
| SCHEMBL3080818 | 0.83 | CES2 (0.32) | TSHR | |
| SCHEMBL2833573 | 0.83 | CES2 (0.32) | TSHR | |
| SCHEMBL2833574 | 0.83 | CES2 (0.32) | TSHR | |
| SCHEMBL17940494 | 0.83 | CES2 (0.32) | TSHR | |
| SCHEMBL17940485 | 0.83 | CES2 (0.32) | TSHR | |
| SCHEMBL13021369 | 0.83 | CES2 (0.32) | TSHR | |
| SCHEMBL9283100 | 0.79 | TDP1 (0.43) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008040951-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2008-04-10 | — | — | WO | disclosed |