Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327903 | 0.84 | — | — | |
| SCHEMBL16705751 | 0.84 | — | — | |
| SCHEMBL11078516 | 0.84 | — | — | |
| SCHEMBL16938658 | 0.83 | TDP1 (0.41) | TDP1TRPA1PPARAALDH1A1PPARG | |
| SCHEMBL4729241 | 0.79 | TDP1 (0.38) | TDP1ALDH1A1 | |
| SCHEMBL4729239 | 0.79 | TDP1 (0.38) | TDP1ALDH1A1 | |
| SCHEMBL13180066 | 0.79 | TDP1 (0.38) | TDP1ALDH1A1 | |
| SCHEMBL16784061 | 0.78 | ALDH1A1 (0.48) | TDP1PPARAOXER1ALDH1A1FFAR1 | |
| SCHEMBL870003 | 0.78 | — | — | |
| SCHEMBL7057099 | 0.77 | ALDH1A1 (0.55) | TDP1TRPA1PPARAOXER1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681582-A1 | PYRAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-15 | — | — | EP | disclosed |