Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 6/20 | 0.41 |
| ▸ | FABP3 | P05413 | 5/20 | 0.41 |
| ▸ | FABP7 | O15540 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | EDNRA | P25101 | 3/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | EDNRB | P24530 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729434 | 1.00 | MEN1 (0.43) | MEN1KMT2AUSP2FABP5FABP3 | |
| SCHEMBL7836631 | 0.80 | ALDH1A1 (0.51) | MEN1KMT2AUSP2FABP5FABP7 | |
| SCHEMBL7836638 | 0.80 | ALDH1A1 (0.51) | MEN1KMT2AUSP2FABP5FABP7 | |
| SCHEMBL15713298 | 0.80 | ALDH1A1 (0.51) | MEN1KMT2AUSP2FABP5FABP7 | |
| SCHEMBL18091184 | 0.80 | ALDH1A1 (0.51) | MEN1KMT2AUSP2FABP5FABP7 | |
| SCHEMBL8548435 | 0.77 | KDM4E (0.41) | NR3C1KDM4EGAAALDH1A1MAPT | |
| SCHEMBL6937090 | 0.75 | CHRNA7 (0.42) | MEN1KMT2AEDNRACYP2D6GAA | |
| SCHEMBL9690184 | 0.75 | FABP3 (0.46) | MEN1KMT2AUSP2FABP5FABP3 | |
| SCHEMBL9061428 | 0.75 | MEN1 (0.39) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL10477591 | 0.74 | FABP3 (0.45) | MEN1KMT2AUSP2FABP5FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008054233-A2 | PROCESS FOR THE PREPARATION OF DOCETAXEL | INSTYTUT FARMACEUTYCZNY (PL) | 2008-05-08 | — | — | WO | claimed |
| WO-2008054233-A2 | PROCESS FOR THE PREPARATION OF DOCETAXEL | INSTYTUT FARMACEUTYCZNY (PL) | 2008-05-08 | — | — | WO | disclosed |