Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27388087 | 0.84 | CYP2D6 (0.53) | CHRNA7CYP2D6SMN1; SMN2TSHRPOLB | |
| SCHEMBL7836631 | 0.76 | ALDH1A1 (0.51) | CYP2D6SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL7836638 | 0.76 | ALDH1A1 (0.51) | CYP2D6SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL15713298 | 0.76 | ALDH1A1 (0.51) | CYP2D6SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL18091184 | 0.76 | ALDH1A1 (0.51) | CYP2D6SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL8863060 | 0.76 | EPHX1 (0.37) | CHRNA7CYP2D6EPHX1SMN1; SMN2TSHR | |
| SCHEMBL8143137 | 0.76 | EPHX1 (0.37) | CHRNA7CYP2D6EPHX1SMN1; SMN2TSHR | |
| SCHEMBL8476572 | 0.76 | EPHX1 (0.37) | CHRNA7CYP2D6EPHX1SMN1; SMN2TSHR | |
| SCHEMBL4729434 | 0.75 | MEN1 (0.43) | CYP2D6MEN1KMT2APOLBTDP1 | |
| SCHEMBL4729436 | 0.75 | MEN1 (0.43) | CYP2D6MEN1KMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370541-A1 | METHOD OF PREPARATION OF PACLITAXEL (TAXOL) USING 3-(ALK-2-YNYLOXY) CARBONYL-5-OXAZOLIDINE CARBOXYLIC ACID | Dabur India Limited (IN) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002066448-A1 | METHOD OF PREPARATION OF PACLITAXEL (TAXOL) USING 3-(ALK-2-YNYLOXY) CARBONYL-5-OXAZOLIDINE CARBOXYLIC ACID | DABUR INDIA LIMITED (IN) | 2002-08-29 | — | — | WO | disclosed |