Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728695 | 0.90 | MTNR1A (0.50) | MTNR1ASMYD3CREBBPBRD4HTR1A | |
| SCHEMBL7951734 | 0.86 | MTNR1A (0.55) | MTNR1ASMYD3CREBBPBRD4HTR2A | |
| SCHEMBL4045997 | 0.84 | MTNR1A (0.55) | MTNR1ASMYD3CREBBPBRD4HTR1A | |
| SCHEMBL2124605 | 0.83 | MTNR1A (0.52) | MTNR1ASMYD3CREBBPBRD4HTR1A | |
| SCHEMBL4128722 | 0.83 | MTNR1A (0.53) | MTNR1ACREBBPBRD4HTR1ADRD3 | |
| SCHEMBL18668694 | 0.81 | MTNR1A (0.46) | MTNR1ASMYD3CREBBPHTR2A | |
| SCHEMBL22977707 | 0.81 | MTNR1A (0.52) | MTNR1ACREBBPBRD4DRD3 | |
| SCHEMBL29593079 | 0.81 | MTNR1A (0.52) | MTNR1ACREBBPBRD4DRD3 | |
| SCHEMBL8553887 | 0.81 | MTNR1A (0.52) | MTNR1ACREBBPBRD4DRD3 | |
| SCHEMBL4138599 | 0.80 | MTNR1A (0.57) | MTNR1ASMYD3CREBBPBRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008042735-A1 | TETRAHYDROQUINOLINE, INDOLINE, AND RELATED ANILINE DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXAN METHYLAMINES | WYETH (US) | 2008-04-10 | — | — | WO | disclosed |