Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 5/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2925561 | 0.81 | HDAC4 (0.64) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL7413228 | 0.81 | MAPT (0.48) | HDAC4HDAC1HDAC8MAPTTP53 | |
| SCHEMBL7413232 | 0.81 | MAPT (0.48) | HDAC4HDAC1HDAC8MAPTTP53 | |
| SCHEMBL5655190 | 0.80 | CTSK (0.48) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL5654573 | 0.79 | CTSK (0.45) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL27676034 | 0.79 | CTSK (0.48) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL27676035 | 0.79 | CTSK (0.48) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL5970266 | 0.79 | HDAC4 (0.54) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL1255732 | 0.79 | CTSS (0.62) | HDAC8MAPTTP53CTSKCTSS | |
| SCHEMBL7208633 | 0.79 | HDAC4 (0.53) | HDAC4HDAC1HDAC3HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050161-A2 | PEPTIDES FOR ACTIVATION OF ANGIOGENESIS, PHARMACEUTICAL COMPOUNDS CONTAINING SAME AND USE OF THESE COMPOUNDS | BIOSTATIN GYÓGYSZERKUTATÓ-FEJLESZTÖ KFT. (HU) | 2008-05-02 | — | — | WO | claimed |
| WO-2008050161-A2 | PEPTIDES FOR ACTIVATION OF ANGIOGENESIS, PHARMACEUTICAL COMPOUNDS CONTAINING SAME AND USE OF THESE COMPOUNDS | BIOSTATIN GYÓGYSZERKUTATÓ-FEJLESZTÖ KFT. (HU) | 2008-05-02 | — | — | WO | disclosed |