Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112111 | 0.89 | AOC3 (0.44) | AOC3SLC6A4SLC6A3ADRB2NISCH | |
| SCHEMBL2279691 | 0.82 | AOC3 (0.42) | AOC3SLC6A4KAT2BOPRM1LMNA | |
| SCHEMBL1443955 | 0.81 | HRH1 (0.59) | AOC3NISCHHTR2AHRH1TAAR1 | |
| SCHEMBL19376998 | 0.81 | NISCH (0.52) | AOC3SLC6A4SLC6A3ADRB2NISCH | |
| SCHEMBL2277962 | 0.79 | AOC3 (0.42) | AOC3SLC6A4SLC6A3ADRB2HTR2A | |
| SCHEMBL4739377 | 0.78 | AOC3 (0.44) | AOC3SLC6A4SLC6A3ADRB2HTR2A | |
| SCHEMBL11566936 | 0.76 | ADRB2 (0.48) | AOC3SLC6A4SLC6A3ADRB2HTR2A | |
| SCHEMBL19402470 | 0.75 | AOC3 (0.44) | AOC3SLC6A4SLC6A3ADRB2NISCH | |
| SCHEMBL27807862 | 0.73 | AOC3 (0.52) | AOC3SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL13493150 | 0.73 | SLC6A4 (0.46) | SLC6A4SLC6A3ADRB2HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057543-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2008-05-15 | — | — | WO | disclosed |