Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279691 | 0.89 | AOC3 (0.42) | AOC3BRD4LMNASMN1; SMN2OPRM1 | |
| SCHEMBL2277962 | 0.82 | AOC3 (0.42) | AOC3LMNASMN1; SMN2OPRM1CHRM2 | |
| SCHEMBL9613800 | 0.81 | AOC3 (0.44) | AOC3OPRM1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL188906 | 0.81 | CHRNB2 (0.38) | AOC3SMN1; SMN2TSHRL3MBTL1OPRK1 | |
| SCHEMBL6112111 | 0.81 | AOC3 (0.44) | AOC3LMNASMN1; SMN2OPRM1SLC6A4 | |
| SCHEMBL11298724 | 0.80 | OPRM1 (0.46) | AOC3OPRM1SLC6A2SLC6A4 | |
| SCHEMBL12071516 | 0.80 | CHRNB2 (0.56) | AOC3LMNAOPRM1CHRM2SLC6A2 | |
| SCHEMBL5398515 | 0.80 | CHRNB2 (0.56) | AOC3LMNAOPRM1CHRM2SLC6A2 | |
| SCHEMBL9995387 | 0.80 | CHRNB2 (0.56) | AOC3LMNAOPRM1CHRM2SLC6A2 | |
| SCHEMBL28144244 | 0.80 | CHRNB2 (0.56) | AOC3LMNAOPRM1CHRM2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081477-A1 | 3-ARYLOXY 3-SUBSTITUTED PROPANAMINES | NATCO PHARMA LIMITED (IN) | 2008-07-10 | — | — | WO | disclosed |