Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 16/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852418 | 0.86 | KDM4E (0.76) | KDM4EHSD17B10ALDH1A1TSHRPOLB | |
| SCHEMBL830750 | 0.85 | KDM4E (0.74) | KDM4EHSD17B10ALDH1A1TSHRPOLB | |
| SCHEMBL2384053 | 0.82 | KDM4E (0.70) | KDM4EHSD17B10ALDH1A1TSHRPOLB | |
| Hydrochloric Acid SCHEMBL5492081 | 0.81 | KDM4E (0.68) | KDM4EHSD17B10ALDH1A1TSHRPOLB | |
| SCHEMBL27979659 | 0.80 | KDM4E (0.85) | KDM4EHSD17B10ALDH1A1TSHRPOLB | |
| SCHEMBL23951452 | 0.77 | TRPV1 (0.56) | KDM4EHSD17B10ALDH1A1TSHRMAPK1 | |
| SCHEMBL1575067 | 0.75 | KDM4E (0.60) | KDM4EHSD17B10ALDH1A1TSHRPOLB | |
| Piperidine SCHEMBL29006137 | 0.75 | KDM4E (0.73) | KDM4EHSD17B10ALDH1A1TSHRPOLB | |
| SCHEMBL2656688 | 0.74 | KDM4E (0.62) | KDM4EHSD17B10ALDH1A1TSHRPOLB | |
| SCHEMBL1575064 | 0.74 | KDM4E (0.62) | KDM4EHSD17B10ALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064054-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-29 | — | — | WO | claimed |
| WO-2008064054-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |